Side effects Ozempic
This page has been reviewed by
Dr. Nicolette Lammers.
Side effects Ozempic
Like all medicines, Ozempic can cause side effects, although not everybody gets them.
Serious side effects
Common (may affect up to 1 in 10 people treated)
- Complications of diabetic eye disease (retinopathy) – You should talk to your doctor if you experience eye problems such as blurred vision during treatment with this medicine.
Occasionally (may affect up to 1 in 100 people treated)
- Inflamed pancreas (acute pancreatitis), which can cause persistent, severe pain in the abdomen and back. See a doctor immediately if you notice these symptoms.
Rare (may affect up to 1 in 1,000 people treated)
- Severe allergic reactions (anaphylactic reactions, angioedema). You must seek immediate medical attention and inform your doctor immediately if you experience symptoms such as breathing problems, swelling of the face, lips, tongue and/or throat with difficulty in swallowing and accelerated heartbeat.
Not known (frequency cannot be estimated based on available data)
- Intestinal obstruction. A severe form of constipation with additional symptoms such as abdominal pain, flatulence, vomiting, etc.
Other side effects
Very common (may affect more than 1 in 10 people treated)
- Nausea – this usually subsides over time
- Diarrhea – this usually subsides over time
- Low blood sugar (hypoglycemia) when using this medicine together with a medicine containing sulfonylurea or insulin.
Common (may affect up to 1 in 10 people treated)
- Vomiting
- Low blood sugar (hypoglycemia) when using this medicine together with oral diabetes medicines other than sulfonylurea or insulin.
The warning signs of hypoglycemia can occur suddenly. They may include cold sweat, cool pale skin, headache, fast heartbeat, nausea or severe hunger, blurred vision, tiredness or weakness, nervousness, anxiety or confusion, difficulty concentrating or trembling. Your doctor will tell you how to treat hypoglycemia and what to do if you notice these warning signs. Hypoglycemia is more likely to occur if you are also taking a sulfonylurea or using insulin. Your doctor may reduce your dose of these medicines before you start treatment with this medicine.
- Indigestion
- Inflammation of the stomach lining (“gastritis”) – symptoms include stomach pain, nausea or vomiting
- Heartburn – also known as “gastroesophageal reflux disease” (GERD)
- Stomach ache
- bloated belly
- Constipation
- Belching
- Gallstones
- Dizziness
- Tiredness
- Weight loss
- reduced appetite
- Flatulence (bloating)
- Increase in pancreatic enzymes (such as lipase and amylase)
Occasionally (may affect up to 1 in 100 people treated)
- Changes in the perception of taste
- Fast pulse
- Reactions at the injection site – such as bruising, pain, skin irritation, itching and skin rash
- Allergic reactions such as skin rash, itching or hives
- Delay in gastric emptying