Side effects Saxenda
This page has been reviewed by
Dr. Nicolette Lammers.
Side effects Saxenda
Like all medicines, Saxenda can cause side effects, although not everybody gets them.
Serious side effects
Severe allergic reactions (anaphylaxis) have rarely been reported in patients using Saxenda. However, if you experience symptoms such as breathing problems, swelling of the throat and face and an accelerated heartbeat, you should consult your doctor immediately.
Cases of pancreatitis (inflammation of the pancreas) have occasionally been reported in patients using Saxenda. Pancreatitis is a serious, potentially life-threatening condition. Discontinue treatment with Saxenda and contact a doctor immediately if you notice any of the following serious side effects:
- Severe and persistent pain in the abdomen (upper abdominal area), which can radiate into your back, as well as nausea and vomiting, as this can be a sign of an inflamed pancreas (pancreatitis).
Other side effects
Very common (may affect more than 1 in 10 people treated)
- Nausea
- Vomiting
- Diarrhea (diarrhea)
- Constipation
– these usually disappear after a few days or weeks
Common (may affect up to 1 in 10 people treated)
- Gastrointestinal complaints such as: Indigestion (dyspepsia), gastritis, stomach pain, upper abdominal discomfort, heartburn, bloating, flatulence, belching, dry mouth
- Feeling weak or tired
- Changed taste sensations
- Dizziness
- Sleep disorders – occur mainly in the first 3 months of treatment.
- Gallstones
- Reactions at the injection site (such as bruising, pain, skin irritation, itching and skin rash)
- Low blood sugar (hypoglycemia)
The warning signs of hypoglycemia can occur suddenly. They may include cold sweat, cool pale skin, headache, fast heartbeat, nausea or severe hunger, blurred vision, tiredness or weakness, nervousness, anxiety or confusion, difficulty concentrating or trembling. Your doctor will tell you how to treat hypoglycemia and what to do if you notice these warning signs. Hypoglycemia is more likely to occur if you are also taking a sulfonylurea or using insulin. Your doctor may reduce your dose of these medicines before you start treatment with this medicine.
Occasionally (may affect up to 1 in 100 people treated)
- Fluid loss (dehydration) – more likely to occur at the start of treatment and may be due to vomiting, nausea and diarrhea.
- Gallbladder inflammation
- Allergic reactions, such as skin rash
- General malaise
- Increased pulse
Rare (may affect 1 to 10 people in 10,000 treated)
- Impaired kidney function
- Acute kidney failure – signs may include a reduction in the amount of urine, a metallic taste in the mouth and the rapid appearance of bruising.
FAQ's Saxenda
How much weight can you lose with Saxenda?
On average, patients lose about 1 kg per week with Saxenda. However, the result varies from individual to individual and depends heavily on the combination with a long-term lifestyle change. Treatment should be discontinued if at least 5% of the original body weight has not been lost after 12 weeks of the maximum daily dose of 3.0 mg.
Who can prescribe Saxenda?
Saxenda may only be prescribed by a doctor, either after a physical or online consultation.
How quickly does Saxenda / liraglutide work?
The Saxenda dosage is gradually increased over 4 weeks. Patients often report a rapid effect on the feeling of hunger and satiety, but mild side effects such as nausea may occur initially. If no weight loss of at least 5% is achieved after 12 weeks at the daily dose of 3.0 mg, treatment is usually discontinued.
How long does a Saxenda pen last?
A prefilled Saxenda pen contains 18 mg liraglutide. At a maintenance dose of 3.0 mg per day, one pen is sufficient for 6 injections, i.e. 6 days. Saxenda is available in packs of 1, 3 or 5 pens, although not all pack sizes are available on the market.
How long can you use Saxenda?
There is no maximum duration of use for Saxenda. You can use it as long as you are not taking other medications that conflict with it or do not develop contraindications.
Saxenda reduces your appetite and makes you feel full, making it easier to change your lifestyle and give up unhealthy habits. In the best case scenario, you will use Saxenda to achieve your desired weight and at the same time develop a healthy lifestyle that enables you to maintain your weight without medication.